The science of androgenic alopecia

By and far, androgenic alopecia passed through all the versatile civilizations of history from the greatest to the most trifle and everything in between. Feeding on the youth and the hairline of the young to grow the veneer of mystery that neither advanced nor conventional science could penetrate. the science of androgenic alopecia the science of androgenic alopecia the science of androgenic alopecia

In more prosaic language, for a condition that has inflicted, consistently, feelings of anxiety on the individuals affected by it throughout history, a remedy for the age-old conundrum that has never been greeted with open arms but rather with hostility, is still under progress. From natural herbs to surgical treatments, prayers and sage, spiritual and medical, the left and the right have been proposed as a solution, and yet due to the reticent characteristics of the condition, a permanent solution is merely an approaching concept quivering on the horizon.

Hair loss treatments have evolved to offer the best possibilities to counteract the effects of the androgenic alopecia in accordance with the data collected about its characteristics. However, to date, no potion or procedure could possibly revive the miniaturized follicular units or stop the progression of the symptoms.

Androgenic alopecia, the molecular mechanism

Like a jigsaw puzzle, the full picture of the cellular machination of androgenic alopecia is missing vital pieces.  What is thus far decoded constitutes that androgenic alopecia is a condition that occurs as a result of two varying traits in follicular units: androgen sensitivity and androgen resistance. The designated response to androgens is a subject of genetic predisposition.

A stronger version of testosterone DHT triggers a cascade of the cellular activity responsible for the miniaturization of follicular units. Androgen sensitive follicular units have a higher number of the 5-alpha reductase enzyme which is responsible for catalyzing the conversion of testosterone to DHT. As a consequence, androgen-sensitive follicular units are susceptible to miniaturization due to the increased levels of DHT.

The missing jigsaw puzzle in this scenario is the polar opposite events DHT stimulate in follicular units based on their location in the body. How DHT promotes growth in body follicular units while promoting destruction in scalp follicular units is not yet known.

The best current treatments for hair loss

Androgenic alopecia ramifies into subcategories of male and female pattern hair loss. In the former, hair loss is predictable and systematic. In the latter, however, the pattern of hair loss is diffused. Owing to the different characteristic of the subcategories, their treatments differ.

Male pattern hair loss is reversible with hair transplants. Whereas female pattern hair loss is ideally treated via minoxidil.

In closing

To have a free personal consultation with a medical specialist to inquire about your case, contact Vera Clinic.

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