{"id":168956,"date":"2026-05-18T11:58:46","date_gmt":"2026-05-18T08:58:46","guid":{"rendered":"https:\/\/www.veraclinic.net\/?p=168956"},"modified":"2026-05-18T11:58:46","modified_gmt":"2026-05-18T08:58:46","slug":"%d8%b9%d9%84%d8%a7%d8%ac-%d8%aa%d8%b3%d8%a7%d9%82%d8%b7-%d8%a7%d9%84%d8%b4%d8%b9%d8%b1-pp405","status":"publish","type":"post","link":"https:\/\/www.veraclinic.net\/ar\/%d8%b9%d9%84%d8%a7%d8%ac-%d8%aa%d8%b3%d8%a7%d9%82%d8%b7-%d8%a7%d9%84%d8%b4%d8%b9%d8%b1-pp405\/","title":{"rendered":"\u0645\u0627 \u0647\u0648 \u0639\u0644\u0627\u062c \u062a\u0633\u0627\u0642\u0637 \u0627\u0644\u0634\u0639\u0631 PP405: \u0643\u064a\u0641 \u062a\u0639\u064a\u062f \u0647\u0630\u0647 \u0627\u0644\u062c\u0632\u064a\u0626\u0629 \u0645\u0646 \u062c\u0627\u0645\u0639\u0629 \u0643\u0627\u0644\u064a\u0641\u0648\u0631\u0646\u064a\u0627 \u0641\u064a \u0644\u0648\u0633 \u0623\u0646\u062c\u0644\u0648\u0633 \u062a\u0646\u0634\u064a\u0637 \u0627\u0644\u062e\u0644\u0627\u064a\u0627 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\u0627\u0644\u0646\u0645\u0648 \u0627\u0644\u0646\u0634\u0637.<\/p><p> \u0648\u0627\u0644\u0646\u062a\u064a\u062c\u0629 \u0647\u064a \u0641\u0626\u0629 \u062c\u062f\u064a\u062f\u0629 \u0645\u0646 \u0627\u0644\u0639\u0644\u0627\u062c\u0627\u062a <strong>\u0627\u0644\u0642\u0627\u0626\u0645\u0629 \u0639\u0644\u0649 \u0627\u0644\u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u062c\u0630\u0639\u064a\u0629 \u0644\u062a\u062c\u062f\u064a\u062f \u0627\u0644\u0634\u0639\u0631\u060c<\/strong> \u0642\u0627\u062f\u0631\u0629 \u0639\u0644\u0649 \u0645\u0639\u0627\u0644\u062c\u0629 <a href=\"https:\/\/www.veraclinic.net\/hair-loss\/\">\u062a\u0633\u0627\u0642\u0637 \u0627\u0644\u0634\u0639\u0631<\/a> <strong>\u0627\u0644\u0646\u0627\u062a\u062c \u0639\u0646 \u0627\u0644\u0635\u0644\u0639 \u0627\u0644\u0648\u0631\u0627\u062b\u064a<\/strong> \u062f\u0648\u0646 \u0622\u062b\u0627\u0631 \u062c\u0627\u0646\u0628\u064a\u0629 \u062c\u0647\u0627\u0632\u064a\u0629.<\/p><p> <strong>\u0643\u064a\u0641 \u064a\u0645\u0643\u0646\u0643 \u0625\u0639\u0627\u062f\u0629 \u062a\u0646\u0634\u064a\u0637 \u0628\u0635\u064a\u0644\u0627\u062a \u0627\u0644\u0634\u0639\u0631 \u0628\u0634\u0643\u0644 \u0637\u0628\u064a\u0639\u064a\u061f<\/strong><\/p><p> \u064a\u0645\u0643\u0646\u0643 \u062a\u062d\u0641\u064a\u0632 \u0627\u0644\u0628\u0635\u064a\u0644\u0627\u062a \u0627\u0644\u062e\u0627\u0645\u0644\u0629 \u0628\u0634\u0643\u0644 \u0637\u0628\u064a\u0639\u064a \u0639\u0646 \u0637\u0631\u064a\u0642 <strong>\u062a\u0639\u0632\u064a\u0632 \u0639\u0645\u0644\u064a\u0629 \u0627\u0644\u0623\u064a\u0636 \u0627\u0644\u062e\u0644\u0648\u064a \u0641\u064a\u0647\u0627<\/strong> \u061b \u0643\u0645\u0627 \u0647\u0648 \u0627\u0644\u062d\u0627\u0644 \u0645\u0639 \u0639\u0644\u0627\u062c \u062a\u0633\u0627\u0642\u0637 \u0627\u0644\u0634\u0639\u0631 PP405\u060c \u0627\u0644\u0630\u064a \u064a\u0632\u064a\u062f <strong>\u0645\u0646 \u062a\u062d\u0644\u0644 \u0627\u0644\u062c\u0644\u0648\u0643\u0648\u0632<\/strong> \u0641\u064a \u0627\u0644\u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u062c\u0630\u0639\u064a\u0629 \u0644\u0628\u0635\u064a\u0644\u0627\u062a \u0627\u0644\u0634\u0639\u0631. \u0647\u0630\u0647 \u0627\u0644\u0639\u0645\u0644\u064a\u0629 \u062a\u0639\u064a\u062f \u0625\u064a\u0642\u0627\u0638 \u0627\u0644\u0646\u0645\u0648 \u0628\u062f\u0648\u0646 \u0647\u0631\u0645\u0648\u0646\u0627\u062a \u0623\u0648 \u062c\u0631\u0627\u062d\u0629\u060c \u0628\u0627\u0644\u0627\u0639\u062a\u0645\u0627\u062f \u0639\u0644\u0649 \u0646\u0638\u0627\u0645 \u0627\u0644\u0637\u0627\u0642\u0629 \u0627\u0644\u062a\u062c\u062f\u064a\u062f\u064a\u0629 \u0627\u0644\u062e\u0627\u0635 \u0628\u0627\u0644\u062c\u0633\u0645.<\/p><h2 class=\"gb-headline gb-headline-03617aff gb-headline-text\"> \u0643\u064a\u0641 \u064a\u0639\u0645\u0644 \u0639\u0644\u0627\u062c \u062a\u0633\u0627\u0642\u0637 \u0627\u0644\u0634\u0639\u0631 PP405\u061f<\/h2><p> \u064a\u0639\u0645\u0644 \u0639\u0644\u0627\u062c \u062a\u0633\u0627\u0642\u0637 \u0627\u0644\u0634\u0639\u0631 PP405 \u0639\u0644\u0649 <strong>\u062a\u062d\u0641\u064a\u0632 \u0627\u0644\u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u062c\u0630\u0639\u064a\u0629 \u0644\u0628\u0635\u064a\u0644\u0627\u062a \u0627\u0644\u0634\u0639\u0631<\/strong> \u0645\u0646 \u062e\u0644\u0627\u0644 \u062a\u063a\u064a\u064a\u0631 \u0641\u064a \u0639\u0645\u0644\u064a\u0629 \u0627\u0644\u0623\u064a\u0636 \u0627\u0644\u062e\u0644\u0648\u064a. \u0639\u0646 \u0637\u0631\u064a\u0642 <strong>\u062a\u062b\u0628\u064a\u0637 \u0646\u0627\u0642\u0644 \u0627\u0644\u0628\u064a\u0631\u0648\u0641\u0627\u062a \u0627\u0644\u0645\u064a\u062a\u0648\u0643\u0648\u0646\u062f\u0631\u064a (MPC)<\/strong> \u060c \u0641\u0625\u0646\u0647 \u064a\u0639\u064a\u062f \u062a\u0648\u062c\u064a\u0647 \u0625\u0646\u062a\u0627\u062c \u0627\u0644\u0637\u0627\u0642\u0629 \u0646\u062d\u0648 <strong>\u062a\u062d\u0644\u0644 \u0627\u0644\u0633\u0643\u0631<\/strong> \u060c \u0645\u0645\u0627 \u064a\u062e\u0644\u0642 \u0628\u064a\u0626\u0629 \u0627\u0633\u062a\u0642\u0644\u0627\u0628\u064a\u0629 \u062a\u0639\u064a\u062f \u0628\u062f\u0621 \u062f\u0648\u0631\u0629 \u0646\u0645\u0648 \u0627\u0644\u0634\u0639\u0631. \u062a\u0648\u0641\u0631 \u0647\u0630\u0647 \u0627\u0644\u0639\u0645\u0644\u064a\u0629 <strong>\u0625\u0639\u0627\u062f\u0629 \u0646\u0645\u0648 \u0627\u0644\u0634\u0639\u0631 \u0639\u0628\u0631 \u0627\u0644\u0637\u0627\u0642\u0629 \u0627\u0644\u062e\u0644\u0648\u064a\u0629<\/strong> \u060c \u0645\u0645\u0627 \u064a\u0648\u0642\u0638 \u0627\u0644\u0628\u0635\u064a\u0644\u0627\u062a \u0627\u0644\u062e\u0627\u0645\u0644\u0629 \u0627\u0644\u062a\u064a \u0643\u0627\u0646\u062a \u063a\u064a\u0631 \u0646\u0634\u0637\u0629 \u0628\u0633\u0628\u0628 \u0627\u0644\u0634\u064a\u062e\u0648\u062e\u0629 \u0623\u0648 \u0627\u0644\u0625\u0634\u0627\u0631\u0627\u062a \u0627\u0644\u0623\u0646\u062f\u0631\u0648\u062c\u064a\u0646\u064a\u0629. <\/p><figure class=\"gb-block-image gb-block-image-175f6809\"><img loading=\"lazy\" decoding=\"async\" width=\"2446\" height=\"1557\" alt=\" PP405 \u0639\u0644\u0627\u062c \u062a\u0633\u0627\u0642\u0637 \u0627\u0644\u0634\u0639\u0631\" class=\"gb-image gb-image-175f6809\" src=\"https:\/\/www.veraclinic.net\/wp-content\/uploads\/2025\/10\/Minoxidil.webp\" title=\" \u0645\u064a\u0646\u0648\u0643\u0633\u064a\u062f\u064a\u0644\" srcset=\"https:\/\/www.veraclinic.net\/wp-content\/uploads\/2025\/10\/Minoxidil.webp 2446w, https:\/\/www.veraclinic.net\/wp-content\/uploads\/2025\/10\/Minoxidil-300x191.webp 300w, https:\/\/www.veraclinic.net\/wp-content\/uploads\/2025\/10\/Minoxidil-1024x652.webp 1024w, https:\/\/www.veraclinic.net\/wp-content\/uploads\/2025\/10\/Minoxidil-768x489.webp 768w, https:\/\/www.veraclinic.net\/wp-content\/uploads\/2025\/10\/Minoxidil-1536x978.webp 1536w, https:\/\/www.veraclinic.net\/wp-content\/uploads\/2025\/10\/Minoxidil-2048x1304.webp 2048w\" sizes=\"auto, (max-width: 2446px) 100vw, 2446px\" \/><\/figure><p> \u0639\u0644\u0649 \u0639\u0643\u0633 \u0627\u0644\u0637\u0631\u0642 \u0627\u0644\u0647\u0631\u0645\u0648\u0646\u064a\u0629 \u0623\u0648 \u0627\u0644\u062c\u0631\u0627\u062d\u064a\u0629\u060c \u064a\u0639\u0645\u0644 \u0639\u0644\u0627\u062c PP405 \u0643\u0639\u0644\u0627\u062c <strong>\u0644\u0641\u0642\u062f\u0627\u0646 \u0627\u0644\u0634\u0639\u0631 \u0627\u0644\u0623\u064a\u0636\u064a<\/strong> \u061b \u0641\u0647\u0648 \u064a\u0639\u064a\u062f \u0634\u062d\u0646 \u0646\u0638\u0627\u0645 \u0627\u0644\u0637\u0627\u0642\u0629 \u0627\u0644\u062f\u0627\u062e\u0644\u064a\u0629 \u0644\u0644\u0628\u0635\u064a\u0644\u0629 \u0644\u062a\u0639\u0632\u064a\u0632 <strong>\u062a\u062c\u062f\u064a\u062f \u0627\u0644\u0628\u0635\u064a\u0644\u0629<\/strong> \u0628\u0634\u0643\u0644 \u0637\u0628\u064a\u0639\u064a\u060c \u0648\u0627\u0633\u062a\u0639\u0627\u062f\u0629 \u0627\u0644\u0643\u062b\u0627\u0641\u0629 \u0648\u0627\u0644\u062d\u064a\u0648\u064a\u0629 \u0645\u0646 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\u0627\u0644\u062e\u0627\u0645\u0644\u0629. \u062a\u0642\u0648\u0645 \u062c\u0632\u064a\u0626\u0627\u062a PP405 \u0628\u0630\u0644\u0643 \u0639\u0646 \u0637\u0631\u064a\u0642 <strong>\u062a\u062b\u0628\u064a\u0637 \u0646\u0627\u0642\u0644 \u0627\u0644\u0628\u064a\u0631\u0648\u0641\u0627\u062a \u0627\u0644\u0645\u064a\u062a\u0648\u0643\u0648\u0646\u062f\u0631\u064a (MPC)<\/strong> \u060c \u0645\u0645\u0627 \u064a\u062c\u0628\u0631 \u0627\u0644\u062e\u0644\u0627\u064a\u0627 \u0639\u0644\u0649 \u0625\u0646\u062a\u0627\u062c \u0627\u0644\u0637\u0627\u0642\u0629 \u0645\u0646 \u062e\u0644\u0627\u0644 <strong>\u062a\u062d\u0644\u0644 \u0627\u0644\u0633\u0643\u0631<\/strong> . \u064a\u0624\u062f\u064a \u0647\u0630\u0627 \u0627\u0644\u062a\u0639\u0632\u064a\u0632 \u0641\u064a <strong>\u0627\u0644\u0637\u0627\u0642\u0629 \u0627\u0644\u062e\u0644\u0648\u064a\u0629<\/strong> \u0625\u0644\u0649 \u0625\u0639\u0627\u062f\u0629 \u062a\u0646\u0634\u064a\u0637 \u0627\u0644\u0628\u0635\u064a\u0644\u0627\u062a \u063a\u064a\u0631 \u0627\u0644\u0646\u0634\u0637\u0629\u060c \u0645\u0645\u0627 \u064a\u062a\u064a\u062d <strong>\u0625\u0639\u0627\u062f\u0629 \u0646\u0645\u0648 \u0627\u0644\u0634\u0639\u0631 \u0639\u0628\u0631 \u0627\u0644\u0637\u0627\u0642\u0629 \u0627\u0644\u062e\u0644\u0648\u064a\u0629<\/strong> \u0648\u064a\u062f\u0641\u0639 <strong>\u062a\u062c\u062f\u064a\u062f \u0627\u0644\u0628\u0635\u064a\u0644\u0627\u062a<\/strong> \u0628\u0627\u0644\u0643\u0627\u0645\u0644 \u062f\u0648\u0646 \u0623\u062f\u0648\u064a\u0629 \u0647\u0631\u0645\u0648\u0646\u064a\u0629 \u0623\u0648 \u062c\u0631\u0627\u062d\u0629.<\/p><h3 class=\"gb-headline gb-headline-2364c497 gb-headline-text\"> \u0645\u062a\u0649 \u0633\u064a\u0643\u0648\u0646 \u0639\u0644\u0627\u062c \u062a\u0633\u0627\u0642\u0637 \u0627\u0644\u0634\u0639\u0631 PP405 \u0645\u062a\u0627\u062d\u064b\u0627\u061f<\/h3><p> <strong>\u0645\u0646 \u0627\u0644\u0645\u062a\u0648\u0642\u0639 \u0623\u0646 \u064a\u0635\u0644 \u0639\u0644\u0627\u062c \u062a\u0633\u0627\u0642\u0637 \u0627\u0644\u0634\u0639\u0631 PP405 \u0625\u0644\u0649 \u0627\u0644\u0623\u0633\u0648\u0627\u0642 \u062d\u0648\u0627\u0644\u064a \u0639\u0627\u0645 2027<\/strong> \u060c \u0628\u0639\u062f \u0627\u0644\u0627\u0646\u062a\u0647\u0627\u0621 \u0645\u0646 <strong>\u0627\u0644\u0645\u0631\u062d\u0644\u0629 \u0627\u0644\u062b\u0627\u0646\u064a\u0629 (\u0623) \u0645\u0646 \u0627\u0644\u062a\u062c\u0627\u0631\u0628 \u0627\u0644\u0633\u0631\u064a\u0631\u064a\u0629<\/strong> \u0627\u0644\u062d\u0627\u0644\u064a\u0629 <strong>\u0648\u0627\u0644\u0645\u0631\u062d\u0644\u0629 \u0627\u0644\u062b\u0627\u0644\u062b\u0629 \u0627\u0644\u0645\u062e\u0637\u0637 \u0644\u0647\u0627 \u0641\u064a \u0639\u0627\u0645 2026.<\/strong> \u0648\u0642\u062f \u0623\u0638\u0647\u0631 \u0627\u0644\u0639\u0644\u0627\u062c\u060c \u0627\u0644\u0630\u064a \u0637\u0648\u0631\u062a\u0647 \u0634\u0631\u0643\u062a\u0627 <strong>Pelage Pharmaceuticals<\/strong> \u0648 <strong>UCLA<\/strong> \u060c \u0628\u0627\u0644\u0641\u0639\u0644 \u0646\u062a\u0627\u0626\u062c \u0645\u0628\u0643\u0631\u0629 \u0642\u0648\u064a\u0629: \u0641\u064a \u062f\u0631\u0627\u0633\u0629 \u0627\u0644\u0645\u0631\u062d\u0644\u0629 \u0627\u0644\u062b\u0627\u0646\u064a\u0629 (\u0623)\u060c <strong>\u062d\u0642\u0642 31 \u0628\u0627\u0644\u0645\u0627\u0626\u0629 \u0645\u0646 \u0627\u0644\u0645\u0634\u0627\u0631\u0643\u064a\u0646 \u0632\u064a\u0627\u062f\u0629 \u062a\u0632\u064a\u062f \u0639\u0646 20 \u0628\u0627\u0644\u0645\u0627\u0626\u0629 \u0641\u064a \u0643\u062b\u0627\u0641\u0629 \u0627\u0644\u0634\u0639\u0631 \u0641\u064a \u063a\u0636\u0648\u0646 \u062b\u0645\u0627\u0646\u064a\u0629 \u0623\u0633\u0627\u0628\u064a\u0639<\/strong> \u060c \u0628\u064a\u0646\u0645\u0627 \u0644\u0645 \u062a\u064f\u0638\u0647\u0631 \u0645\u062c\u0645\u0648\u0639\u0629 \u0627\u0644\u062f\u0648\u0627\u0621 \u0627\u0644\u0648\u0647\u0645\u064a \u0623\u064a \u0632\u064a\u0627\u062f\u0629 ( <em>Dermatology Times<\/em> , 2024).<\/p><p> \u0633\u062a\u0624\u0643\u062f \u0627\u0644\u0645\u0631\u062d\u0644\u0629 \u0627\u0644\u062a\u0627\u0644\u064a\u0629 \u0633\u0644\u0627\u0645\u0629 \u0627\u0644\u0645\u0646\u062a\u062c \u0639\u0644\u0649 \u0627\u0644\u0645\u062f\u0649 \u0627\u0644\u0637\u0648\u064a\u0644 \u0648\u0627\u062a\u0633\u0627\u0642 \u0625\u0639\u0627\u062f\u0629 \u0627\u0644\u0646\u0645\u0648 \u0642\u0628\u0644 \u0627\u0644\u0633\u0639\u064a \u0644\u0644\u062d\u0635\u0648\u0644 \u0639\u0644\u0649 \u0645\u0648\u0627\u0641\u0642\u0629 \u0625\u062f\u0627\u0631\u0629 \u0627\u0644\u063a\u0630\u0627\u0621 \u0648\u0627\u0644\u062f\u0648\u0627\u0621. \u0648\u062d\u062a\u0649 \u0630\u0644\u0643 \u0627\u0644\u062d\u064a\u0646\u060c <strong>\u064a\u0638\u0644 PP405 \u063a\u064a\u0631 \u0645\u062a\u0627\u062d \u062a\u062c\u0627\u0631\u064a\u064b\u0627<\/strong> \u0648\u0644\u0627 \u064a\u0645\u0643\u0646 \u0627\u0644\u0648\u0635\u0648\u0644 \u0625\u0644\u064a\u0647 \u0625\u0644\u0627 \u0645\u0646 \u062e\u0644\u0627\u0644 \u062f\u0631\u0627\u0633\u0627\u062a \u0645\u0633\u062c\u0644\u0629 \u0645\u062b\u0644 <em>ClinicalTrials.gov ID NCT06393452.<\/em><\/p><p> <strong>\u0647\u0644 \u064a\u062c\u0628 \u0623\u0646 \u0623\u0646\u062a\u0638\u0631 \u062d\u062a\u0649 \u0645\u0648\u0639\u062f PP405 \u0623\u0645 \u0623\u0628\u062f\u0623 \u0627\u0644\u0639\u0644\u0627\u062c \u0627\u0644\u0622\u0646\u061f<\/strong><\/p><p> \u0625\u0630\u0627 \u0643\u0627\u0646 \u062a\u0633\u0627\u0642\u0637 \u0634\u0639\u0631\u0643 \u064a\u062a\u0641\u0627\u0642\u0645\u060c \u0641\u0645\u0646 \u0627\u0644\u0623\u0641\u0636\u0644 \u0627\u0644\u0628\u062f\u0621 \u0641\u064a <strong>\u0627\u0644\u0639\u0644\u0627\u062c\u0627\u062a \u0627\u0644\u0645\u062b\u0628\u062a\u0629 \u0633\u0631\u064a\u0631\u064a\u064b\u0627<\/strong> \u0627\u0644\u0622\u0646 \u0628\u062f\u0644\u0627\u064b \u0645\u0646 \u0627\u0646\u062a\u0638\u0627\u0631 \u0625\u0635\u062f\u0627\u0631 PP405. \u0644\u0627 \u062a\u0632\u0627\u0644 \u0627\u0644\u062c\u0632\u064a\u0626\u0629 \u0641\u064a <strong>\u0627\u0644\u062a\u062c\u0627\u0631\u0628 \u0627\u0644\u0633\u0631\u064a\u0631\u064a\u0629<\/strong> \u0648\u0644\u0646 \u062a\u0643\u0648\u0646 \u0645\u062a\u0627\u062d\u0629 \u0642\u0628\u0644 <strong>\u0639\u0627\u0645 2027<\/strong> \u0639\u0644\u0649 \u0623\u0642\u0631\u0628 \u062a\u0642\u062f\u064a\u0631.<\/p><p> \u062a\u064f\u0638\u0647\u0631 \u0627\u0644\u062e\u064a\u0627\u0631\u0627\u062a \u0627\u0644\u062d\u0627\u0644\u064a\u0629 \u0645\u062b\u0644 <strong>\u0627\u0644\u0645\u064a\u0646\u0648\u0643\u0633\u064a\u062f\u064a\u0644<\/strong> \u0623\u0648 <strong>\u0627\u0644\u0641\u064a\u0646\u0627\u0633\u062a\u0631\u0627\u064a\u062f<\/strong> \u0623\u0648 <strong>\u0627\u0644\u0639\u0644\u0627\u062c\u0627\u062a \u0627\u0644\u0642\u0627\u0626\u0645\u0629 \u0639\u0644\u0649 \u0627\u0644\u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u062c\u0630\u0639\u064a\u0629<\/strong> \u0645\u062b\u0644 <strong>\u0639\u0644\u0627\u062c \u0623\u0648\u0643\u0633\u064a \u0643\u064a\u0648\u0631<\/strong> \u0641\u064a <strong>\u0639\u064a\u0627\u062f\u0629 \u0641\u064a\u0631\u0627<\/strong> \u0628\u0627\u0644\u0641\u0639\u0644 \u0646\u062a\u0627\u0626\u062c \u0642\u0627\u0628\u0644\u0629 \u0644\u0644\u0642\u064a\u0627\u0633 \u0648\u0628\u064a\u0627\u0646\u0627\u062a \u0633\u0644\u0627\u0645\u0629 \u0645\u062b\u0628\u062a\u0629. \u064a\u0633\u0627\u0639\u062f \u0627\u0644\u0628\u062f\u0621 \u0645\u0628\u0643\u0631\u064b\u0627 \u0641\u064a \u0627\u0644\u062d\u0641\u0627\u0638 \u0639\u0644\u0649 \u0627\u0644\u0628\u0635\u064a\u0644\u0627\u062a \u0627\u0644\u0645\u0648\u062c\u0648\u062f\u0629\u060c \u0648\u0627\u0644\u062a\u064a \u0642\u062f \u064a\u0639\u064a\u062f PP405 \u062a\u062c\u062f\u064a\u062f\u0647\u0627 \u0644\u0627\u062d\u0642\u064b\u0627 \u0628\u0634\u0643\u0644 \u0623\u0643\u062b\u0631 \u0641\u0639\u0627\u0644\u064a\u0629 \u0628\u0645\u062c\u0631\u062f \u062a\u0648\u0641\u0631\u0647.<\/p><h4 class=\"gb-headline gb-headline-d158b2d6 gb-headline-text\"> \u0643\u0645 \u0633\u062a\u0628\u0644\u063a \u062a\u0643\u0644\u0641\u0629 PP405\u061f<\/h4><p> <strong>\u0644\u0645 \u064a\u062a\u0645 \u0627\u0644\u0625\u0639\u0644\u0627\u0646 \u0639\u0646 \u0633\u0639\u0631 \u0631\u0633\u0645\u064a\u060c<\/strong> \u0648\u0644\u0643\u0646 \u0645\u0646 \u0627\u0644\u0645\u062a\u0648\u0642\u0639 \u0623\u0646 \u064a\u062a\u0631\u0627\u0648\u062d \u0633\u0639\u0631 PP405 <strong>\u0628\u064a\u0646 1500 \u0648 3000 \u062f\u0648\u0644\u0627\u0631 \u0644\u0643\u0644 \u062f\u0648\u0631\u0629 \u0639\u0644\u0627\u062c\u064a\u0629<\/strong> \u0628\u0645\u062c\u0631\u062f \u0625\u0637\u0644\u0627\u0642\u0647\u060c \u0648\u0630\u0644\u0643 \u0628\u0646\u0627\u0621\u064b \u0639\u0644\u0649 \u0646\u0645\u0627\u0630\u062c \u062a\u0633\u0639\u064a\u0631 \u0627\u0644\u062a\u0643\u0646\u0648\u0644\u0648\u062c\u064a\u0627 \u0627\u0644\u062d\u064a\u0648\u064a\u0629 \u0627\u0644\u062d\u0627\u0644\u064a\u0629 \u0644\u0644\u0639\u0644\u0627\u062c\u0627\u062a \u0627\u0644\u0645\u0648\u0636\u0639\u064a\u0629 \u0627\u0644\u0645\u062a\u0642\u062f\u0645\u0629.<\/p><h2 class=\"gb-headline gb-headline-3166cc0e gb-headline-text\"> \u0647\u0644 \u0639\u0644\u0627\u062c \u062a\u0633\u0627\u0642\u0637 \u0627\u0644\u0634\u0639\u0631 PP405 \u0641\u0639\u0627\u0644 \u062d\u0642\u064b\u0627\u061f<\/h2><p> <strong>\u0646\u0639\u0645\u060c \u0627\u0644\u0623\u062f\u0644\u0629 \u0627\u0644\u0645\u0628\u0643\u0631\u0629 \u0625\u064a\u062c\u0627\u0628\u064a\u0629\u060c \u0648\u0644\u0643\u0646 \u0645\u0627 \u0647\u064a \u0627\u0644\u0646\u062a\u0627\u0626\u062c \u0637\u0648\u064a\u0644\u0629 \u0627\u0644\u0645\u062f\u0649<\/strong> \u0644\u0639\u0644\u0627\u062c \u062a\u0633\u0627\u0642\u0637 \u0627\u0644\u0634\u0639\u0631 \u0644\u0639\u0627\u0645 2025\u061f<br\/> <strong>\u063a\u064a\u0631 \u0645\u0639\u0631\u0648\u0641\u0629.<\/strong> \u0641\u064a \u0627\u0644\u0645\u0631\u062d\u0644\u0629 2\u0623\u060c \u062d\u0642\u0642 <strong>31%<\/strong> \u0645\u0646 \u0627\u0644\u0645\u0634\u0627\u0631\u0643\u064a\u0646 \u0627\u0644\u0630\u064a\u0646 \u0639\u0648\u0644\u062c\u0648\u0627 <strong>\u0632\u064a\u0627\u062f\u0629 \u0641\u064a \u0643\u062b\u0627\u0641\u0629 \u0627\u0644\u0634\u0639\u0631 \u0628\u0646\u0633\u0628\u0629 \u062a\u0632\u064a\u062f \u0639\u0646 20% \u0641\u064a \u0627\u0644\u0623\u0633\u0628\u0648\u0639 \u0627\u0644\u062b\u0627\u0645\u0646<\/strong> \u0645\u0642\u0627\u0628\u0644 <strong>0%<\/strong> \u0645\u0645\u0646 \u062a\u0646\u0627\u0648\u0644\u0648\u0627 \u0627\u0644\u062f\u0648\u0627\u0621 \u0627\u0644\u0648\u0647\u0645\u064a\u061b \u0648\u0643\u0627\u0646 \u0627\u0644\u062f\u0648\u0627\u0621 <strong>\u062c\u064a\u062f \u0627\u0644\u062a\u062d\u0645\u0644<\/strong> \u060c \u0648\u062a\u0628\u062f\u0623 \u0627\u0644\u0645\u0631\u062d\u0644\u0629 3 \u0641\u064a <strong>\u0639\u0627\u0645 2026.<\/strong> \u0648\u0644\u0627 \u064a\u0632\u0627\u0644 \u064a\u062a\u0639\u064a\u0646 \u0625\u062b\u0628\u0627\u062a \u0627\u0644\u0645\u062a\u0627\u0646\u0629 \u0639\u0644\u0649 \u0627\u0644\u0645\u062f\u0649 \u0627\u0644\u0637\u0648\u064a\u0644 \u0648\u0627\u0644\u0633\u0644\u0627\u0645\u0629 \u0648\u0627\u0644\u062c\u0631\u0639\u0627\u062a \u0641\u064a \u062a\u062c\u0627\u0631\u0628 \u0623\u0643\u0628\u0631.<\/p><p> <strong>\u0627\u0644\u0625\u064a\u062c\u0627\u0628\u064a\u0627\u062a<\/strong><\/p><ul class=\"wp-block-list\"><li> \u063a\u064a\u0631 \u0647\u0631\u0645\u0648\u0646\u064a\u060c \u0645\u0648\u0636\u0639\u064a\u061b \u064a\u0633\u062a\u0647\u062f\u0641 <strong>\u0646\u0627\u0642\u0644 \u0627\u0644\u0628\u064a\u0631\u0648\u0641\u0627\u062a \u0627\u0644\u0645\u064a\u062a\u0648\u0643\u0648\u0646\u062f\u0631\u064a (MPC)<\/strong> \u0648\u0627\u0633\u062a\u0642\u0644\u0627\u0628 \u0627\u0644\u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u062c\u0630\u0639\u064a\u0629.<\/li><li> \u0625\u0634\u0627\u0631\u0629 \u0633\u0631\u064a\u0639\u0629: \u0646\u0645\u0648 \u0645\u0644\u062d\u0648\u0638 \u0625\u062d\u0635\u0627\u0626\u064a\u064b\u0627 \u0628\u062d\u0644\u0648\u0644 \u0627\u0644\u0623\u0633\u0628\u0648\u0639 \u0627\u0644\u062b\u0627\u0645\u0646 \u0641\u064a \u0627\u0644\u0645\u0631\u062d\u0644\u0629 2\u0623.<\/li><li> \u063a\u064a\u0631 \u0645\u062a\u0648\u0641\u0631 \u062a\u062c\u0627\u0631\u064a\u064b\u0627\u061b \u064a\u0645\u0643\u0646 \u0627\u0644\u0648\u0635\u0648\u0644 \u0625\u0644\u064a\u0647 \u0641\u0642\u0637 \u0639\u0628\u0631 \u0627\u0644\u062a\u062c\u0627\u0631\u0628 (\u0639\u0644\u0649 \u0633\u0628\u064a\u0644 \u0627\u0644\u0645\u062b\u0627\u0644\u060c <strong>NCT06393452<\/strong> ).<\/li><li> \u0627\u0644\u0641\u0639\u0627\u0644\u064a\u0629\/\u0627\u0644\u0633\u0644\u0627\u0645\u0629 \u0639\u0644\u0649 \u0627\u0644\u0645\u062f\u0649 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\u0627\u0644\u0623\u0633\u0627\u0633\u064a\u0629<\/strong><\/td><td> <strong>\u0645\u0633\u062a\u0648\u0649 \u0627\u0644\u0623\u062f\u0644\u0629<\/strong><\/td><td> <strong>\u0627\u0644\u0648\u0636\u0639 \u0627\u0644\u062a\u0646\u0638\u064a\u0645\u064a<\/strong><\/td><td> <strong>\u0646\u0627\u0641\u0630\u0629 \u0627\u0644\u062a\u0623\u062b\u064a\u0631 \u0627\u0644\u0646\u0645\u0648\u0630\u062c\u064a\u0629<\/strong><\/td><td> <strong>\u0627\u0644\u0633\u0644\u0627\u0645\u0629\/\u0645\u0644\u0627\u062d\u0638\u0627\u062a<\/strong><\/td><\/tr><tr><td> <strong>PP405<\/strong><\/td><td> <strong>\u062a\u062b\u0628\u064a\u0637 MPC \u2190 \u0632\u064a\u0627\u062f\u0629 \u062a\u062d\u0644\u0644 \u0627\u0644\u062c\u0644\u0648\u0643\u0648\u0632 \u2190 \u062a\u0646\u0634\u064a\u0637 \u0627\u0644\u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u062c\u0630\u0639\u064a\u0629 \u0644\u0628\u0635\u064a\u0644\u0627\u062a \u0627\u0644\u0634\u0639\u0631<\/strong><\/td><td> \u0627\u0644\u0645\u0631\u062d\u0644\u0629 2\u0623: <strong>31%<\/strong> \u062d\u0642\u0642\u0648\u0627 <strong>\u0643\u062b\u0627\u0641\u0629 >20% \u0641\u064a \u0627\u0644\u0623\u0633\u0628\u0648\u0639 \u0627\u0644\u062b\u0627\u0645\u0646<\/strong> \u0645\u0642\u0627\u0628\u0644 0% \u0644\u0644\u0645\u062c\u0645\u0648\u0639\u0629 \u0627\u0644\u0636\u0627\u0628\u0637\u0629.<\/td><td> \u0641\u064a \u0627\u0644\u062a\u062c\u0627\u0631\u0628\u061b \u0627\u0644\u0645\u0631\u062d\u0644\u0629 \u0627\u0644\u062b\u0627\u0644\u062b\u0629 \u0645\u062e\u0637\u0637 \u0644\u0647\u0627 \u0641\u064a \u0639\u0627\u0645 2026<\/td><td> \u0625\u0634\u0627\u0631\u0629 \u0628\u0639\u062f 8 \u0623\u0633\u0627\u0628\u064a\u0639 \u062a\u0642\u0631\u064a\u0628\u064b\u0627 (\u062a\u062c\u0631\u0628\u0629)<\/td><td> \u0627\u0644\u0628\u064a\u0627\u0646\u0627\u062a \u0627\u0644\u0623\u0648\u0644\u064a\u0629: \u062c\u064a\u062f \u0627\u0644\u062a\u062d\u0645\u0644\u061b \u0627\u0644\u0628\u064a\u0627\u0646\u0627\u062a \u0637\u0648\u064a\u0644\u0629 \u0627\u0644\u0623\u062c\u0644 \u0642\u064a\u062f \u0627\u0644\u0627\u0646\u062a\u0638\u0627\u0631.<\/td><\/tr><tr><td> <strong>\u0641\u064a\u0646\u0627\u0633\u062a\u0631\u0627\u064a\u062f (1 \u0645\u0644\u063a \u0639\u0646 \u0637\u0631\u064a\u0642 \u0627\u0644\u0641\u0645)<\/strong><\/td><td> <strong>\u062a\u062b\u0628\u064a\u0637 \u062f\u064a\u0647\u062f\u0631\u0648\u062a\u0633\u062a\u0648\u0633\u062a\u064a\u0631\u0648\u0646 (5-\u0623\u0644\u0641\u0627-\u0631\u064a\u062f\u0648\u0643\u062a\u0627\u0632 \u0627\u0644\u0646\u0648\u0639 \u0627\u0644\u062b\u0627\u0646\u064a)<\/strong><\/td><td> \u062a\u064f\u0638\u0647\u0631 \u0627\u0644\u0639\u062f\u064a\u062f \u0645\u0646 \u0627\u0644\u062a\u062c\u0627\u0631\u0628 \u0627\u0644\u0633\u0631\u064a\u0631\u064a\u0629 \u0627\u0644\u0639\u0634\u0648\u0627\u0626\u064a\u0629 \u0632\u064a\u0627\u062f\u0629 \u0641\u064a \u0639\u062f\u062f \u0627\u0644\u0634\u0639\u0631 \u0648\u062a\u0628\u0637\u0626 \u0645\u0646 \u062a\u0633\u0627\u0642\u0637\u0647 \u0639\u0644\u0649 \u0645\u062f\u0649 \u0633\u0646\u0629 \u0625\u0644\u0649 \u0633\u0646\u062a\u064a\u0646.<\/td><td> \u0645\u0639\u062a\u0645\u062f \u0645\u0646 \u0625\u062f\u0627\u0631\u0629 \u0627\u0644\u063a\u0630\u0627\u0621 \u0648\u0627\u0644\u062f\u0648\u0627\u0621 (\u0644\u0644\u0631\u062c\u0627\u0644)<\/td><td> \u062a\u0638\u0647\u0631 \u0627\u0644\u0646\u062a\u0627\u0626\u062c \u0627\u0644\u0645\u0631\u0626\u064a\u0629 \u062e\u0644\u0627\u0644 3-6 \u0623\u0634\u0647\u0631\u061b \u0648\u062a\u0633\u062a\u0645\u0631 \u0645\u0639 \u0627\u0644\u0627\u0633\u062a\u062e\u062f\u0627\u0645 \u0627\u0644\u0645\u062a\u0648\u0627\u0635\u0644.<\/td><td> \u0627\u0644\u0622\u062b\u0627\u0631 \u0627\u0644\u062c\u0627\u0646\u0628\u064a\u0629 \u0627\u0644\u062c\u0646\u0633\u064a\u0629\/\u0627\u0644\u0646\u0641\u0633\u064a\u0629 \u0627\u0644\u062a\u064a \u0646\u0648\u0642\u0634\u062a \u0641\u064a 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<strong>\u0648\u0646\u0645\u0648\u064b\u0627 \u0625\u0636\u0627\u0641\u064a\u064b\u0627 \u0644\u0644\u0634\u0639\u0631 \u0628\u0646\u0633\u0628\u0629 45% \u062a\u0642\u0631\u064a\u0628\u064b\u0627 \u0645\u0642\u0627\u0628\u0644 2%<\/strong> \u0628\u0639\u062f 48 \u0623\u0633\u0628\u0648\u0639\u064b\u0627.<\/td><td> \u0645\u0639\u062a\u0645\u062f \u0645\u0646 \u0625\u062f\u0627\u0631\u0629 \u0627\u0644\u063a\u0630\u0627\u0621 \u0648\u0627\u0644\u062f\u0648\u0627\u0621 (FDA) \u0644\u0644\u0627\u0633\u062a\u062e\u062f\u0627\u0645 \u0628\u062f\u0648\u0646 \u0648\u0635\u0641\u0629 \u0637\u0628\u064a\u0629<\/td><td> \u063a\u0627\u0644\u0628\u064b\u0627 \u0645\u0627 \u064a\u0633\u062a\u0642\u0631 \u062a\u0633\u0627\u0642\u0637 \u0627\u0644\u0634\u0639\u0631 \u0641\u064a \u063a\u0636\u0648\u0646 8-12 \u0623\u0633\u0628\u0648\u0639\u064b\u0627\u061b \u0648\u064a\u0638\u0647\u0631 \u0627\u0644\u062a\u0623\u062b\u064a\u0631 \u0627\u0644\u0643\u0627\u0645\u0644 \u0641\u064a \u063a\u0636\u0648\u0646 24-48 \u0623\u0633\u0628\u0648\u0639\u064b\u0627.<\/td><td> \u0642\u062f \u064a\u062d\u062f\u062b \u062a\u0647\u064a\u062c \u0641\u064a \u0641\u0631\u0648\u0629 \u0627\u0644\u0631\u0623\u0633\/\u0641\u0631\u0637 \u0627\u0644\u0634\u0639\u0631.<\/td><\/tr><tr><td> <strong>RU58841<\/strong><\/td><td> <strong>\u0645\u0636\u0627\u062f \u0627\u0644\u0623\u0646\u062f\u0631\u0648\u062c\u064a\u0646 \u0627\u0644\u0645\u0648\u0636\u0639\u064a \u063a\u064a\u0631 \u0627\u0644\u0633\u062a\u064a\u0631\u0648\u064a\u062f\u064a (\u062d\u0627\u0635\u0631 \u0645\u0633\u062a\u0642\u0628\u0644\u0627\u062a \u0627\u0644\u0623\u0646\u062f\u0631\u0648\u062c\u064a\u0646)<\/strong><\/td><td> \u0645\u0627 \u0642\u0628\u0644 \u0627\u0644\u0633\u0631\u064a\u0631\u064a\u0629 \u0648\u0642\u0635\u0635\u064a\u0629\u061b <strong>\u0644\u0627 \u062a\u0648\u062c\u062f \u062a\u062c\u0627\u0631\u0628 \u0633\u0631\u064a\u0631\u064a\u0629 \u0639\u0634\u0648\u0627\u0626\u064a\u0629 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\u0648\u0628\u0639\u062f \u0645\u0646 \u0627\u0644\u0645\u0634\u0627\u0631\u0643\u064a\u0646 \u0641\u064a \u0627\u0644\u062a\u062c\u0627\u0631\u0628 \u0627\u0644\u0633\u0631\u064a\u0631\u064a\u0629 <strong>\u0632\u064a\u0627\u062f\u0629 \u0648\u0627\u0636\u062d\u0629 \u0641\u064a \u0627\u0644\u0643\u062b\u0627\u0641\u0629<\/strong> \u060c \u0648\u0633\u0645\u0627\u0643\u0629 \u0627\u0644\u0634\u0639\u064a\u0631\u0627\u062a\u060c \u0648\u062a\u062d\u0633\u0646\u064b\u0627 \u0641\u064a \u062a\u063a\u0637\u064a\u0629 \u0641\u0631\u0648\u0629 \u0627\u0644\u0631\u0623\u0633 \u0628\u0639\u062f <strong>8-12 \u0623\u0633\u0628\u0648\u0639\u064b\u0627<\/strong> \u0645\u0646 \u0627\u0644\u0627\u0633\u062a\u062e\u062f\u0627\u0645 \u0627\u0644\u0645\u0648\u0636\u0639\u064a \u0627\u0644\u064a\u0648\u0645\u064a. \u0646\u0645\u0637 \u0625\u0639\u0627\u062f\u0629 \u0627\u0644\u0646\u0645\u0648 \u0644\u0646\u062a\u0627\u0626\u062c PP405 <strong>\u0645\u0646\u062a\u0634\u0631 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